ABSTRACT
Objective:To investigate the effect of botulinum toxin type A on children with odorihidrosis.Methods:From March 2017 to February 2021, 121 children with odorihidrosis, including 48 males and 73 females, aged 13 to 17 (15.9±1.2) years, were admitted to the Burn and Plastic Surgery Department of the 980 Hospital of PLA. There were 24 cases in mild group, 50 cases in moderate group and 47 cases in severe group. Botulinum toxin A was injected into 20-50 points on each side, and 1 U was injected into each point. The total amount of botulinum toxin A was 50-100 U on both sides.Results:Three groups of children were evaluated for efficacy, 24 cases of mild group was significantly effective in 23 cases, accounting for 95.8%. In the moderate group, 46 (92.0%) of 50 cases showed obvious effect. 49 cases (98.0%) were effective; In the severe group, 40 cases (85.1%) showed obvious effect and 45 cases (95.7%) were effective. Three groups of children with different efficacy had no statistical significance ( P>0.05). The significant efficiency in mild and moderate groups was higher than that in severe group, and the difference was statistically significant ( P<0.05). Conclusions:Botulinum toxin type A is effective in the treatment of children with mild and moderate bromhidrosis, and is worthy of clinical application.
ABSTRACT
Objecttive To explore the effect of medical polyacrylamide hydrogel on the ultrastructure of human fibroblasts.Methods 22 hyperplastic fibropeplos around the medical polyacrylamide hydrogel in mammaries after augmentation mammoplasty by injection of medical polyacrylamide hydrogel were obtained by operations.The tissues were observed with the transmission electron microscope and at the same time photographs taken.Results Most of cell organoles dissolved and disappeared;Most of the cristaes and membranes of mitochondria coalesced or disappeared;rough endoplasmic reticulum expanded.Most of the cristaes and membranes coalesced or/and disappeared.The phenomenon of shed particle was observed in some of the rough endoplasmic reticulum.Conclusion The medical polyacrylamide hydrogel obviously injures the ultrastructures of human fibroblasts.